High sodium/potassium
ratio and high blood pressure
An increased caloric intake is often associated
with a high salt consumption. The influence of the dietary sodium/potassium
ratio for manifestation of high blood pressure is controversial. It remains
undefined whether within a given population an increased sodium intake leads
to a statistically provable blood pressure increase. Food with a low sodium/potassium
ratio and a low caloric density should nonetheless be preferred. It is recommended
to reduce the salt intake from the usual 150-200 mmol/day of affluent societies
to at least 100 mmol/day that does not result in an impairment of taste. There
is increasing evidence that a raised sodium intake leads to an increased sympathetic
outflow of the brain originating from centers in the brain stem (1). Both,
a too high caloric and sodium intake could by a common pathway accelerate
the manifestation of hypertension.
1. Pawloski-Dahm CM, Gordon
FJ: Increased dietary salt sensitizes vasomotor neurons of the rostral ventrolateral
medulla. Hypertension 1993;22:929-933